Chemical engineering graduate courses
CE 500 Special Topics in Chemical Engineering
Advanced topics in chemical engineering to meet the needs and
interests of graduate students.
CE 505 Special Topics: Molecular Imaging: Fundamental Bioengineering Principles
Molecular imaging (MI) is a highly interdisciplinary and rapidly emerging field in which fundamental biological processes are visualized, quantified, and analyzed in living subjects. As such, MI has become an indispensable tool for biomedical research, for the development of diagnostics, for nano, molecular , biologic, cellular, and tissue–based therapeutics, and for drug discovery. Rather than focus on the wide applications of MI (i.e. Oncology, Cardiology, Inflammation, Angiogenesis, Gene and Cell Therapy), this course is designed to teach fundamental engineering aspects drawing from the science and engineering, and then considering clinical applications. The interdisciplinary subjects to be covered include fundamental aspects of chemical engineering (mass balances, transport, and kinetics), Physics (optics, biophotonics, ultrasound, nuclear and MRI physics), Radiology (imaging instrumentation, modalities, image reconstruction and analysis), Chemistry (Synthetic and Radiochemistry), Biology (Biotechnology, Protein Engineering, Molecular Biology, Biochemistry, Cell Biology), Clinical Medicine (Pharmacology, Pathology), and Translational Medicine. By the end of the class, the student will understand: 1) how to read, analyze, and interpret molecular imaging literature, 2) how to be able to design and test molecular imaging strategies for a particular problem of interest, 3) how to create, interpret and analyze molecular images, 4) strengths and limitations of each approach, 5) emerging and advanced topics, 6) general knowledge of the clinical and industrial aspects of the MI.
CE 508 Metabolic Engineering
This course deals with the analysis and medication of metabolic
pathways. It provides an integration and quantification approach
towards metabolism and cell physiology. Areas that will be covered
in this course include a review of cellular metabolism, comprehensive
models for cellular reactions, regulation of metabolic pathways,
examples of pathway manipulations (metabolic engineering in practice),
metabolic flux analysis and metabolic control analysis. Some concepts
of bioinformatics in a way that relate with cell metabolism studies,
will also be introduced.
CE 509 Transport Phenomena I
Introduction to the principles of transport phenomena, particularly
fluid mechanics. Fully developed laminar flows. Navier-Stokes
equations derived from the point of view of momentum transport.
Boundary layer concepts and assumptions discussed and applied
to specific configurations. Creeping flows in relation to specific
applications. Mathematical techniques, including orthogonal function
expansions and similarity-type solutions. Buoyancy-driven flows.
Applications in reverse osmosis, crystallization, and chromatography.
Asymptotic solutions valid for high Prandtl and Schmidt numbers.
Phenomenological theories of turbulence. Free surface and conduit
CE 510 Transport Phenomena II
(Continuation of CE 509.) Emphasis on heat and mass transfer.
Convection. Energy and convective diffusion equations, formulation
of proper boundary conditions for various physical situations.
Combined modes of transfer. Steady and unsteady state conduction
and diffusion. Moving boundary problems.
CE 515 Phase Equilibrium and Staged Operations
Theoretical and computational methods necessary to characterize systems by their vapor-liquid phase relationships. Behavior in ideal binary to multicomponent real systems. State calculations from single ideal cases to multi-component fractionation methods. Equipment parameters and design methods.
CE 517 Bioengineering Principles
This is an advanced bioengineering course designed to teach engineering graduate students fundamental concepts that will assist them to transition from traditional engineering based education to bioengineering research. To achieve this goal, the class seeks to educate the students on fundamental as well as practical knowledge that are directly relevant to the type of research that is conducted in bioengineering laboratories.
CE 523 Fundamentals of Green Engineering for Chemical Engineers
This course will discuss topics relevant to chemical engineering
problems of cleaning gaseous, liquid and solid streams. The course
will provide an introduction to environmental cleaning technology
at a senior undergraduate/beginning graduate level. It will provide
students with the knowledge and ability to deal with the daily
practice of chemical engineers in designing clean technological
processes or cope with the waste streams that are not handled
properly in the plant. (Crosslisted with CE 423.) <
CE 525 Advanced Chemical Engineering Thermodynamics
Brief review of classical equilibrium thermodynamics based on
the second law. Statistical concepts helpful in calculating properties
of mixtures. Calculations of phase equilibria in binary and multi-component
systems using modern approaches based on molecular thermodynamics.
CE 526 Statistical Mechanics
A first approach to statistical mechanics and its methods. Ensembles
and the statistical formulation of the laws of thermodynamics.
Mono-and poly-atomic ideal gases. Imperfect gases and graph theory.
Dense liquids, distribution functions, computer simulation techniques.
Lattice models, renormalization group methods. Microscopic dynamics
and transport properties. Inhomogeneous fluids.
CE 527 Colloid and Surface Phenomena
Intermolecular and surface forces. Solid-liquid and liquid-liquid
interfaces: thermodynamics, condensation, capillary action, contact
angles, adsorption from solution, monolayers. Self-assembly in
solution: micelles, bilayers, microemulsions, phase behavior.
Colloidal dispersions: detergency, emulsions, foams, colloidal
stability. (Crosslisted with CE 457).
CE 529 Application and Advanced Topics of Colloid and Surface
Applications of principles of surface chemistry. Chemisorption
and catalysis. Detergency. Emulsion. Flotation. Kinetics of coagulation
processes. Colloidal methods of studying the molecular weight
and shape of polymer molecules and other particles. Polymer adsorption.
Cell membrane structure. Adhesion. Environmental applications.
CE 530 Molecular Simulation
This course will provide students with an understanding of the
methods, capabilities, and limitations of molecular simulation.
It will consist of the following topics: Theory, methods, and
application of molecular simulation. Elementary statistical mechanics.
Molecular modeling. Basic Monte Carlo and molecular dynamics techniques
and ensemble averaging. Evaluation of free energies, phase equilibria,
interfacial properties, and transport and rate coefficients. Applications
to simple and complex fluids and solids. Commercial simulation
CE 531 Chemical Engineering Analysis I
Development and application of mathematical techniques of particular
interest to chemical engineers. Process of formulating mathematical
models for simple chemical processes. Differential equations,
ordinary and partial. Analytical (exact and approximate) methods
of solving equations.
CE 532 Chemical Engineering Analysis II
Computational methods for solving differential equations that
model physical phenomena in chemical engineering.
CE 533 Introduction to Finite Element Methods
Finite element methods will be developed in the general framework
of the weighted residual methods. Basis function (Lagrange, Hermite,
Spline) will be developed in one, two, and three dimensions. Programming
with FEM will be discussed for linear and nonlinear problems as
well as for moving boundary problems. Iterative solution schemes
will be compared and employed. Physical problems will be solved
from the areas of fluid flow, transport phenomena, and reaction
CE 534 Materials Science and Corrosion
Intermolecular and inter-atomic forces; molecular orbitals and
chemical bonds, crystal geometry and defects; metals and alloys;
diffusion, nucleation, and microstructure; phase diagrams and
phase transformations; mechanical properties of materials; polymers;
semiconductors; superconductors; corrosion and electrochemistry.
Includes a lab. (Crosslisted with CE 433).
CE 535 Polymer Science and Engineering I
Introduction to polymers/macromolecules. Classification of polymers
with respect to structure and mechanisms of polymerization reaction.
Relations between chemical structure and physical properties.
Polymer solutions and blends. Mechanical behavior and engineering
properties of polymers.
CE 536 Polymer Science and Engineering II (Polymer Synthesis)
Types of polymers and polymerizations. Step polymerization (kinetics,
crosslinking). Radical chain and emulsion polymerization. Ionic
chain polymerization (cationic, anionic). Chain copolymerization.
Ring-opening polymerization. Reactions of polymers.
CE 537 Polymer Thermodynamics
Chain-like nature of polymers and techniques for the characterization
of polymer molecular weight and size. Statistical thermodynamics
of polymer solutions, phase equilibria in polymer systems. Polymers
in the amorphous, crystalline, or rubber state. Cross-linked polymers
and rubber elasticity.
CE 538 Polymer Rheology
Inelastic and viscoelastic fluids. Structure and flow phenomena
associated with polymeric liquids. Detailed treatment of material
functions and rheometry. Differential integral and rate-type constitutive
equations. Introduction to the molecular treatment of rheology.
Several problems in applied non-Newtonian fluid mechanics.
CE 539 Fundamentals of Polymer Processing
Theory and practice of polymer processing operations. Review
of continuum me chanics and conservation principles for mass,
momen-tum, and energy. Viscometry and rheological equations of
state. Industrially important polymer processes, including single
and twin screw extrusion, wire coating, film blowing, fiber spinning,
blow molding, injection molding, and rotational molding. Mixing,
lubrication theory, and stability of flows.
CE 547 Biochemical Engineering
Advanced treatment of metabolic pathways in prokaryotes and eukaryotes;
fermentor and bioreactor design and operation strategies; bioseparations;
genetic engineering techniques; and models of cellular function. (Crosslisted with CE 446).
CE 548 Cellular & Molecular Bioengineering
This senior undergraduate/beginning level graduate course serves
as an introduction to Biomedical Engineering with emphasis on
vascular engineering. The overall goal is to give students an
understanding of how quantitative approaches can be combined with
biological information to advance knowledge in the areas of thrombosis,
inflammation to biology and cancer metastasis. Emphasis is placed
on cellular and molecular bioengineering methods. (Crosslisted
with CE 448.)
CE 550 Protein Engineering
This course is an introduction to Protein Engineering and Design. The objective of the course is to teach the students to think of protein as an object that can be engineered using molecular tools in order to achieve novel physical and chemical properties. The students first learn the fundamentals of protein structure and how protein structure dictates function. This includes discussions of protein structure, biochemistry and molecular biology techniques, the basics of physical and organic chemistry, and molecular modeling through computer visualization. Additionally, students learn different protein design strategies, including knowledge-based design, computational protein design, and directed evolution, that are commonly used for protein engineering. Examples of engineered proteins with novel structural and functional properties are extensively discussed to illustrate how design principles are applied to real life problems. (Crosslisted with CE 450).
CE 556 Introduction to Aerosol Science
This course will provide students with an introduction to aerosol
science and technology at a senior undergraduate/beginning graduate
level. It will provide students with the knowledge and skills
needed to understand and predict the production, transport, and
other behavior of aerosols and will introduce them to technologies
for producing, measuring, and collecting them. (Crosslisted with
CE 561 Applied Chemical Kinetics
Applications of chemical kinetics, thermodynamics, and transport
phenomena to the design of chemical reactors. More practical than
CE 563 Heterogeneous Catalysis
Catalyst preparation. Newer techniques for surface analysis (ESCA,
AES, SEMEDAX, EXAFS, SIMS). Treatment of mass and heat transfer
effects in catalytic kinetics.
CE 564 Tissue Engineering
Tissue Engineering is a relatively new field that combines knowledge of engineering principles, material science and cell biology to reconstruct tissues ex vivo. It is driven by the rapidly growing need for tissue transplants world-wide. Examples of these technologies that are currently being developed in various laboratories include bioengineered skin, bone, cartilage, blood vessels, heart valves, liver, islets and bone marrow.
In this course we discuss the following topics: (i) the basic scientific principles enabling the field of tissue engineering (cell culture, biology of extracellular matrix molecules, elements of immune reaction to transplants); (ii) engineering fundamentals (biomaterials/scaffolds for tissue growth, engineering the microenvironment for optimal cell organization and function; technologies for spatio-temporal control of cell/tissue organization); (iii) methods for genetic manipulation of cells; and (iv) specific examples of bioengineered tissues including skin, blood vessels, bone and others. The ultimate goal is for the students to understand the main conceptual and technical challenges facing the field of tissue engineering and regenerative medicine and the transition of cell therapies from the laboratory to the clinic.
CE 571 Frontiers of Chemical Technology
Students are exposed to a broad range of industrial problems
and will solve the problems in a project-oriented approach.
CE 580 Nonlinear Analysis
Autonomous and nonautonomous systems; nonlinear ODEs; phase plane
analysis; linear stability theory; Lyapunovs direct method; bifurcation
theory; cusps, isolas, and limit cycles; periodic solutions and
Hopf bifurcation and stability analysis; nonlinear PDEs; pattern
formation in chemical systems; transition to chaos; hydrodynamic
stability. Examples focus on reaction and transport processes.
CE 611, 612 Chemical Engineering Seminar
Graduate students are required to attend weekly seminars presented
by distinguished speakers from academia and industry.
CE 630 & 631 Research Methods in Chemical Engineering,
Parts I & II
This is a two-semester course that aims at training doctoral
graduate students in the methodologies and practices used in chemical
engineering research. Students learn the techniques for formulating,
developing and completing an original research problem in their
respective fields of interest. The course material covers development
of new research ideas, literature search to identify the state
of the art in the specific field, connectivity and cross-fertilization
of ideas, multidisciplinary research, as well as instruction on
the most popular experimental, theoretical and computational techniques
used in chemical engineering research. Students will work on individual
research projects developed during the first semester of the course.
The second semester will focus on obtaining preliminary original
results. Evaluation of student performance will be based on progress
reports and a final report. Oral defense of the final reports
in front of a committee of graduate faculty is required.