Johannes M. Nitsche Professor 507 Furnas Hall (716) 645-2911 ext. 2213 Fax: (716) 645-3822 nitsche@eng.buffalo.edu

Short bio

Research

Publications

Teaching

Chapters in Books

• J.M. Nitsche and G.B. Kasting, "Biophysical Models for Skin Transport and Absorption," In:  M.S. Roberts and K.A. Walers, Eds., Dermal Absorption and Toxicity Assessment, 2nd ed., New York:  Taylor & Francis, (2007; to appear).
• G.B. Kasting, M.A. Miller and J.M. Nitsche, "Absorption and Evaporation of Volatile Compounds Applied to Skin," In: K.A. Walters and M.S. Roberts, Eds., Absorption, Efficacy and Toxicology and Dermatologicals and Cosmoceuticals, New York:  Taylor & Francis, (2007; to appear).
• J.M. Nitsche, Cellular microtransport processes: Intercellular, intracellular, and aggregate behavior. Annu. Rev. Biomed. Eng.1, 463–503 (1999).

Refereed Journal Publications (Recent)

• T.M. Suchyna, J.M. Nitsche, M. Chilton, A.L. Harris, R.D. Veenstra and B.J. Nicholson, Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channels. Biophys. J. 77, 2968–2987 (1999).
• V. Sikavitsas, J.M. Nitsche and T.J. Mountziaris. Transport and kinetic processes underlying biomolecular interactions in the BIACORE optical biosensor. Biotechnol. Prog.18, 885–897 (2002).
• G.B. Kasting, N.D. Barai, T.-F. Wang and J.M. Nitsche. Mobility of Water in Human Stratum Corneum. J. Pharm. Sci.92, 2326–2340 (2003).
• J.M. Nitsche, H.-C. Chang, P.A. Weber and B.J. Nicholson, A transient diffusion model yields unitary gap junctional permeabilities from images of cell-to-cell fluorescent dye transfer between Xenopus oocytes. Biophys. J.86, 2058–2077 (2004).
• P.A. Weber, H.-C. Chang, K.E. Spaeth, J.M. Nitsche and B.J. Nicholson, The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities. Biophys. J. (accepted, to appear, 2004).
• K. Kretsos, G.B. Kasting and J.M. Nitsche, “Distributed Diffusion-Clearance Model for Transient Drug Distribution within the Skin.” J. Pharm. Sci., 93, 2820-2835 (2004).
• T.-F. Wang, G.B. kasting and J.M. Nitsche, "A Multiphase Microscopic Diffusion Model for Stratum Corneum Permeability. I.  Formulation, Solution, and Illustrative Results for Representative Compounds," J. Pharm. Sci., 95, 620-649 (2006).
• J.M. Nitsche, T.-F. Wang and G.B. Kasting, "A Two-Phase Analysis of Solute Partitioning into the Stratum Corneum," J. Pharm. Sci., 95, 649-666 (2006).
• T.-F. Wang, G.B. Kasting and J.M. Nitsche, "A Multiphase Microscopic Diffusion Model for Stratum Corneum Permeability. II.  Estimation of Physicochemical Parameters, and Application to a large Permeability Database," J. Pharm. Sci. (2007).  In Press.

Last Updated: October 2007