The Bioengineering group of CBE is a unique and diverse group of investigators employing engineering fundamentals and biology to:
1. understand basic biological processes e.g. the role of mechanical forces on cell behavior, protein glycosylation, stem cell aging, stem cell differentiation; and
2. develop novel technologies such as production of value-added chemicals, engineering novel proteins with improved properties, development of anti-clotting agents, scale-up production of stem cells for cell therapies and engineering tissues (blood vessels, skin, bone, cartilage) for tissue replacement and regeneration.
UB CBE students not only have access to state of the art research equipment within the bio labs at CBE, but also have access to these facilities and instrumentation:
The Biological Sciences Imaging Facility, which provides optical microscopy, confocal microscopy, and TEM imaging.
The School of Medicine’s Core Facilities, which include analytical chemistry and toxicology, genomics (conventional and next-generation sequencing, transgenics), proteomics (SPR, MALDI-TOF, LC-MS, protein crystallization), flow cytometry, histology, confocal microscopy, TEM imaging, PET/CT imaging, and stem cell culture, banking, and analysis.
The Comparative Medicine Laboratory Animal Facilities, which provide complete services for experiments with small and large animals.
UB CBE's on-site instrumentation includes:
Stelios T. Andreadis
Gene therapy, tissue engineering of skin and blood vessels, controlled protein and gene delivery
Biomedical engineering, cell biomechanics, vascular engineering
Johannes M. Nitsche
Transport phenomena, bioactive surfaces, biological pores, transdermal transport
Sheldon J. Park
Protein engineering, yeast surface display, bioinformatics, molecular dynamic simulations
Cellular, metabolic, natural product biosynthesis, therapies for infectious disease and cancer, and new gene delivery systems
Liver stem cell biology, differentiation, cell therapy, organogenesis, disease modeling, tissue engineering. Multimodality molecular imaging, monitoring molecular events in living subjects.
Dr. Swihart will receive the 2013 Jacob F. Schoellkopf Medal, from the WNY section of the American Chemical Society for his fundamental discoveries in the field of nanoparticle synthesis and processing.
Molecular engineering of novel membrane materials for gas and vapor separations, such as CO2 capture from power plant syngas and flue gas, natural gas purifications, olefin/paraffin separations, and so on.
David Kofke and Andrew Schultz awarded for development of the etomica modules, a community-developed suite of interactive simulations helping students understand molecular origins of macroscopic behaviors. >>
Computational simulation of template-assisted self-assembly of magnetic core-shell nanoparticles into a tapered hexagonal closed-packed multilayed structure compared with corresponding image taken from the literature.